Plant growth promotion rhizobacteria (PGPR) can be applied around the roots of plants and function as biofertilizers, biostimulants, and biopectants. When PGPR improves soil fertility in plant area, the dose of inorganic fertilizers can be lowered. On the other hand, it may also affect the growth of weeds around the crops. The objectives of the research were to study the interaction of PGPR with the dose of inorganic fertilizers on the growth and yield of peanuts, as well as the impact of the PGPR application on the appearance of weeds around the planting area. The results showed that there was a significant interaction of PGPR with the doses of fertilizers on peanut yields. The yield of peanuts was not significantly different from 100% recommended dose (RD) of inorganic fertilizers if 1.0% PGPR was combined with 75 and 50% RD of inorganic fertilizers, and 2.0% PGPR was combined with 75, 50 and 25% RD of inorganic fertilizer. The application of PGPR has no effects on the appearance of weeds in peanut fields. It is concluded that applying PGPR at 1.0% or 2.0% in peanut cultivation in coastal lands of ultisol showed the potential in reducing the need for inorganic fertilizers of nitrogen and phosphor down to 50% or 25%, respectively.